Helps physicians recognize syndromes and syndrome-associated neoplasms and advise treating physicians, patients, and their families on the possibility of a familial syndrome and their risk of developing other tumors

Addresses a wide range of inherited tumor syndromes to increase understanding of the gross and histologic features of syndromic-associated neoplasms as well as associated manifestations

Part I includes nearly 100 detailed chapters describing diagnoses by organ and system associated with familial cancer syndromes; Part II contains more than 80 chapters with detailed descriptions of major inherited syndromes (cross-referenced with diagnoses); and Part III features an updated Molecular Factors Index that includes a complete description of each known gene associated with a familial cancer syndrome

Includes substantial updates throughout, with more than a dozen new chapters, new images and references, updated guidelines and classifications based on the 2025 WHO Classification of Tumours: Genetic Tumour Syndromes, details on the newest familial cancer syndromes, and more

Contains hundreds of tables organized by body part and/or organ system that include selected existing genetic and familial cancers and identified associated genes, clinical features, recognized manifestations, and staging images/microscopic examples

Features nearly 2,300 print and online images, including clinical and radiologic images, algorithms, graphics, gross pathology and histology images, and a wide range of special and immunohistochemical stains and molecular markers―all carefully annotated to highlight the most diagnostically significant factors

Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care

Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date.

Vania Nosé